DIVISION OF PULMONARY & CRITICAL CARE MEDICINE | OHSU

Transforming Pulmonary and Critical Illness Through Clinical Discovery

Directed by Dr. Akram Khan, MBBS, PRISM tests new treatments and therapies for serious lung and critical illnesses at OHSU:

  • Inpatient ICU Trials: Urgent hospital studies for ARDS, sepsis, and life-threatening respiratory failure.

  • Outpatient Clinic Trials: Long-term clinic studies for COPD, chronic lung disease, and lung recovery.

Research

EXTINGUISH Logo
Phase III study evaluating an intravenous administration of mesenchymal stem cell-derived extracellular vesicles vs. placebo for moderate to severe ARDS.
OPTIMIZE Trial Logo VBI-S Logo
Phase IV study assessing Cystatin C and pharmacokinetic profiles of meropenem and cefepime in critically ill adults with antimicrobial-resistant infections.
ANGLE Trial Logo
Comparing the use of a hyperangulated video laryngoscope blade versus a standard geometry video laryngoscope blade during emergency intubation.
SLICC Logo PREVENT-VILI Logo PRACTICAL Logo
Observational study collecting biospecimens via bronchoscopy in ARDS patients to evaluate early onset markers and outcomes.